Gene description for SMAD3
Gene name	SMAD family member 3
Gene symbol	SMAD3
Other names/aliases	HSPC193 HsT17436 JV15-2 LDS1C LDS3 MADH3 hMAD-3 hSMAD3 mad3
Species	Homo sapiens
Experiment description of studies that identified SMAD3 in Lung cancer cells
1 Experiment ID 616 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name NCI-H522 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
2 Experiment ID 894 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - gefitinib-resistant - Rep 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
3 Experiment ID 895 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - gefitinib-resistant - Rep 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%